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Article

Accuracy of an amplicon-sequencing nanopore approach to identify variants in tuberculosis drug-resistance-associated genes.

Microbial genomics - 1 Dec 2021

Mariner-Llicer Carla, Goig Galo A, Zaragoza-Infante Laura, Torres-Puente Manuela, Villamayor Luis, Navarro David, Borras Rafael, Chiner-Oms Álvaro, Comas Iñaki

Abstract excerpt

A rapid and accurate diagnostic assay represents an important means to detect Mycobacterium tuberculosis, identify drug-resistant strains and ensure treatment success. Currently employed techniques to diagnose drug-resistant tuberculosis include slow phenotypic tests or more rapid molecular assays that evaluate a limited range of drugs. Whole-genome-sequencing-based approaches can detect known...

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Identifiers

PMID: 34919513
DOI: 10.1099/mgen.0.000740
PMCID: PMC8767343

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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