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Article

Alu element in the RNA binding motif protein, X-linked 2 (RBMX2) gene found to be linked to bipolar disorder.

PloS one - 1 Jan 2021

Laine Pia, Rowell William J, Paulin Lars, Kujawa Steve, Raterman Denise, Mayhew George, Wendt Jennifer, Burgess Daniel L, Partonen Timo, Paunio Tiina, Auvinen Petri, Ekholm Jenny M

Abstract excerpt

OBJECTIVE: We have used long-read single molecule, real-time (SMRT) sequencing to fully characterize a ~12Mb genomic region on chromosome Xq24-q27, significantly linked to bipolar disorder (BD) in an extended family from a genetic sub-isolate. This family segregates BD in at least four generations with 24 affected individuals. METHODS: We selected 16 family members for targeted sequencing. The selected...

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PMID: 34914762
DOI: 10.1371/journal.pone.0261170
PMCID: PMC8675739

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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