Article
Causal relationships between interleukins, interferons and COVID-19 risk: a Mendelian randomization study.
International journal of environmental health research - 1 May 2024
Wang Chao, Wang Xin, Zhang Sainan, Xu Peigang, Cheng Liang
Abstract excerpt
Observational studies have shown close associations between COVID-19 risk and cytokines, especially interleukins (ILs) and interferons (IFNs). However, the causal relationships between ILs, IFNs and COVID-19 were still unclear. To resolve the problem, we conducted a Mendelian randomization analysis between COVID-19 and 47 cytokines, including 35 ILs and 12 IFNs. First, three methods were applied to estimate...
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