Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A TP53-associated immune prognostic signature for the prediction of the overall survival and therapeutic responses in pancreatic cancer.

Mathematical biosciences and engineering : MBE - 1 Jan 2022

Liu Yi, Cheng Long, Song Xiangyang, Li Chao, Zhang Jiantao, Wang Lei

Abstract excerpt

Pancreatic cancer (PC) is a highly fatal disease correlated with an inferior prognosis. The tumor protein p53 (TP53) is one of the frequent mutant genes in PC and has been implicated in prognosis. We collected somatic mutation data, RNA sequencing data, and clinical information of PC samples in the Cancer Genome Atlas (TCGA) database. TP53 mutation was an independent prognostic predictor of PC patients. According...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Nomograms

Share to Pancreatic and Hepatic Oncology Research

Share to Pancreatic Neoplasms

Share to Prognosis

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 34902987
DOI: 10.3934/mbe.2022010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A TP53-associated immune prognostic signature for the prediction of the overall survival and therapeutic responses in pancreatic cancer.PMID 34902987Read ↗

A novel tp53-associated nomogram to predict the overall survival in patients with pancreatic cancer.Semantic proximity Read ↗

A TP53-Associated Immune Prognostic Signature for the Prediction of Overall Survival and Therapeutic Responses in Muscle-Invasive Bladder Cancer.Semantic proximity Read ↗

Construction of a five-gene prognostic model based on immune-related genes for the prediction of survival in pancreatic cancerSemantic proximity Read ↗

Driver mutation subtypes involve with differentiated immunophenotypes influencing pancreatic cancer outcomes.Semantic proximity Read ↗

A Novel Immune-Related Gene Prognostic Index (IRGPI) in Pancreatic Adenocarcinoma (PAAD) and Its Implications in the Tumor MicroenvironmentSemantic proximity Read ↗

Identification of a novel immune-related gene prognostic index in pancreatic adenocarcinoma and its implication on tumor immunologySemantic proximity Read ↗

Immune landscape and a promising immune prognostic model associated with TP53 in early-stage lung adenocarcinoma.Semantic proximity Read ↗

Tumor-Infiltrating Leukocyte Compositions and Prognostic Immune-Related Genes in Pancreatic Cancer.Semantic proximity Read ↗

Comprehensive Analysis of Clinical Prognosis and Molecular Immune Characterization of TPM4 in Pancreatic CancerSemantic proximity Read ↗

Construction and validation of a TP53-associated immune prognostic model for gastric cancer.Semantic proximity Read ↗

A DNA-Methylation-Driven Genes Based Prognostic Signature Reveals Immune Microenvironment in Pancreatic CancerSemantic proximity Read ↗

A TP53 Related Immune Prognostic Model for the Prediction of Clinical Outcomes and Therapeutic Responses in Lung Adenocarcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.