Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

A DNA-Methylation-Driven Genes Based Prognostic Signature Reveals Immune Microenvironment in Pancreatic Cancer

10 Feb 2022

Abstract excerpt

Pancreatic cancer (PACA), which is characterized by an immunosuppressive nature, remains one of the deadliest malignancies worldwide. Aberrant DNA methylation (DNAm) reportedly influences tumor immune microenvironment. Here, we evaluated the role of DNA methylation driven genes (MDGs) in PACA through integrative analyses of epigenomic, transcriptomic, genomic and clinicopathological data obtained from TCGA, ICGC,...

Source

Identifiers

PMID: 35222383
DOI: 10.3389/fimmu.2022.803962

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A DNA-Methylation-Driven Genes Based Prognostic Signature Reveals Immune Microenvironment in Pancreatic CancerPMID 35222383Read ↗

Identification of a novel immune-related gene prognostic index in pancreatic adenocarcinoma and its implication on tumor immunologySemantic proximity Read ↗

A Novel Immune-Related Gene Prognostic Index (IRGPI) in Pancreatic Adenocarcinoma (PAAD) and Its Implications in the Tumor MicroenvironmentSemantic proximity Read ↗

Tumor-Infiltrating Leukocyte Compositions and Prognostic Immune-Related Genes in Pancreatic Cancer.Semantic proximity Read ↗

m6A Methylation Modification Patterns and Tumor Microenvironment Infiltration Characterization in Pancreatic CancerSemantic proximity Read ↗

Integrated Analysis of Multi-Omics Data to Identify Prognostic Genes for Pancreatic Cancer.Semantic proximity Read ↗

Identification of DNA methylation‑driven genes by integrative analysis of DNA methylation and transcriptome data in pancreatic adenocarcinomaSemantic proximity Read ↗

m1A Regulator ALKBH1 and TRMT10B as Potential Prognostic Biomarkers and Related to Tumor Immune Microenvironment in Pancreatic AdenocarcinomaSemantic proximity Read ↗

m1A Regulator ALKBH1 and TRMT10B as Potential Prognostic Biomarkers and Related to Tumor Immune Microenvironment in Pancreatic AdenocarcinomaSemantic proximity Read ↗

Construction of immune-related signature and identification of S100A14 determining immune-suppressive microenvironment in pancreatic cancerSemantic proximity Read ↗

Profiles and clinical significance of immune cell infiltration in pancreatic adenocarcinomaSemantic proximity Read ↗

The Pyroptosis-Related Signature Predicts Prognosis and Indicates New Treatment Targets in Pancreatic CancerSemantic proximity Read ↗

N6-methyladenosine methylation modification patterns reveal immune profiling in pancreatic adenocarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.