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Article

Construction and validation of a TP53-associated immune prognostic model for gastric cancer.

Genomics - 1 Nov 2020

Nie Kechao, Zheng Zhihua, Wen Yi, Shi Laner, Xu Shjie, Wang Xueqi, Zhou Yingsheng, Fu Bin, Li Xiushen, Deng Zhitong, Pan Jinglin, Jiang Xiaotao, Jiang Kailin, Yan Yanhua, Zhuang Kunhai, Huang Wei, Liu Fengbin, Li Peiwu

Abstract excerpt

Increasing evidence indicates that TP53 mutation impacts the patients' prognosis by regulating the gastric cancer (GC) immunophenotype. An immune prognostic signature (IPS) was constructed based on TP53 status. The effects of the IPS on the immune microenvironment of GC were analyzed. We also constructed a nomogram integrating the IPS and other clinical factors. An IPS was constructed in the TCGA cohort and...

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Identifiers

PMID: 32858135
DOI: 10.1016/j.ygeno.2020.08.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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