Article
A TP53-Associated Immune Prognostic Signature for the Prediction of Overall Survival and Therapeutic Responses in Muscle-Invasive Bladder Cancer.
Frontiers in immunology - 1 Jan 2020
Wu Xiangkun, Lv Daojun, Cai Chao, Zhao Zhijian, Wang Ming, Chen Wenzhe, Liu Yongda
Abstract excerpt
Background: TP53 gene mutation is one of the most common mutations in human bladder cancer (BC) and has been implicated in the progression and prognosis of BC. Methods: RNA sequencing data and TP53 mutation data in different populations and platforms were downloaded from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) database to determine and validate a TP53-associated immune prognostic...
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