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Article

Distinct genetic clusters in HIV-1 CRF01_AE-infected patients induced variable degrees of CD4+ T-cell loss.

mBio - 13 Mar 2024

Li Kang, Chen Huanhuan, Li Jianjun, Feng Yi, Liang Shujia, Rashid Abdur, Liu Meiliang, Li Sisi, Chu Qingfei, Ruan Yuhua, Xing Hui, Lan Guanghua, Qiao Wentao, Shao Yiming

Abstract excerpt

CRF01_AE strains have been shown to form multiple transmission clusters in China, and some clusters have disparate pathogenicity in Chinese men who have sex with men. This study focused on other CRF01_AE clusters prevalent in heterosexual populations. The CD4+ T-cell counts from both cross-section data in National HIV Molecular Epidemiology Survey and seropositive cohort data were used to evaluate the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38385695
DOI: 10.1128/mbio.03349-23
PMCID: PMC10936439

Genes

CD4
CXCR4
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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