The implication of BRAF mutation in advanced colorectal cancer.

doi:10.1007/s11845-021-02689-x

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Article

The implication of BRAF mutation in advanced colorectal cancer.

Irish journal of medical science - 1 Dec 2022

O'Riordan Emma, Bennett Michael William, Daly Louise, Power Derek G

Abstract excerpt

BACKGROUND: Advanced colorectal cancer (CRC) is frequently a lethal disease. Mutations in the BRAF gene is a key driver in CRC pathogenesis and confers a poor prognosis. To date, Irish data on this molecular subtype of CRC is lacking. AIMS: Our aim was to compare the natural history of Irish pati...

Topics

Female
Humans
Colorectal Neoplasms
Mutation
Prognosis
Prospective Studies
Proto-Oncogene Proteins B-raf
Retrospective Studies

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