Article
Genome-wide association study identifies BTNL2 associated with atopic asthma in children.
Medicine - 5 Nov 2021
Kim Soo Yeon, Kim Eun Gyul, Kim Mina, Hong Jung Yeon, Kim Ga Eun, Jung Jae Hwa, Park Mireu, Kim Min Jung, Kim Yoon Hee, Sohn Myung Hyun, Kim Kyung Won
Abstract excerpt
ABSTRACT: Asthma is a heterogeneous disease characterized by chronic airway inflammation with a genetic predisposition. Butyrophilin-like 2 (BTNL2) is a member of the immunoglobulin superfamily that plays an important role in regulating T cell activation and immune homeostasis. Here, we aimed to investigate the association of the genetic variants of BTNL2 with childhood asthma and asthma-related traits by...
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