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MitophAging: Mitophagy in Aging and Disease

15 Apr 2020

Abstract excerpt

Maintaining mitochondrial health is emerging as a keystone in aging and associated diseases. The selective degradation of mitochondria by mitophagy is of particular importance in keeping a pristine mitochondrial pool. Indeed, inherited monogenic diseases with defects in mitophagy display complex multisystem pathologies but particularly progressive neurodegeneration. Fortunately, therapies are being developed that...

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PMID: 32373609
DOI: 10.3389/fcell.2020.00239

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