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Article

Genome-Wide association between EYA1 and Aspirin-induced peptic ulceration.

EBioMedicine - 1 Dec 2021

Bourgeois Stephane, Carr Daniel F, Musumba Crispin O, Penrose Alexander, Esume Celestine, Morris Andrew P, Jorgensen Andrea L, Zhang J Eunice, Pritchard D Mark, Deloukas Panos, Pirmohamed Munir

Abstract excerpt

BACKGROUND: Low-dose aspirin can cause gastric and duodenal ulceration, hereafter called peptic ulcer disease (PUD). Predisposition is thought to be related to clinical and genetic factors; our aim was to identify genetic risk factors associated with aspirin-induced PUD. METHODS: Patients (n=1478) were recruited from 15 UK hospitals. Cases (n=505) were defined as patients with endoscopically confirmed PUD within...

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Identifiers

PMID: 34864618
DOI: 10.1016/j.ebiom.2021.103728
PMCID: PMC8646165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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