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Article

MON-2, a Golgi protein, mediates autophagy-dependent longevity in Caenorhabditis elegans

3 Dec 2021

Abstract excerpt

. Consistently, we showed that mammalian MON2 activated GABARAPL2 through physical interaction, which increased autophagic flux in mammalian cells. Thus, the evolutionarily conserved role of MON2 in trafficking between the Golgi and endosome is an integral part of autophagy-mediated longevity.

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Identifiers

PMID: 34860542
DOI: 10.1126/sciadv.abj8156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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