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Article

Structure and Mutations of SARS-CoV-2 Spike Protein: A Focused Overview.

ACS infectious diseases - 14 Jan 2022

Mehra Rukmankesh, Kepp Kasper P

Abstract excerpt

The spike protein (S-protein) of SARS-CoV-2, the protein that enables the virus to infect human cells, is the basis for many vaccines and a hotspot of concerning virus evolution. Here, we discuss the outstanding progress in structural characterization of the S-protein and how these structures facilitate analysis of virus function and evolution. We emphasize the differences in reported structures and that analysis...

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Identifiers

PMID: 34856799
DOI: 10.1021/acsinfecdis.1c00433

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