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Article

Thyroid Function and the Risk of Alzheimer's Disease: A Mendelian Randomization Study

1 Dec 2021

Abstract excerpt

Background: Observational studies suggest an association between thyroid function and risk of dementia, but the causality and direction of these effects are unclear. We aim to test whether genetically predicted variation within the normal range of thyroid function and hypothyroidism is causally associated with the risk of Alzheimer's disease (AD). Methods: Mendelian randomization (MR) analyses using genetic...

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PMID: 34847795
DOI: 10.1089/thy.2021.0321

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