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Article

Autoimmune thyroid disease is a risk factor for mood disorders, a Mendelian randomization study

11 Mar 2025

Abstract excerpt

BACKGROUND: Observational studies have demonstrated associations between autoimmune thyroid disease and both mood disorders and dementia, but the direction of causality has not been established. METHODS: We employed bidirectional, two-sample Mendelian randomization analyses to assess the causal links between autoimmune thyroid disease (Graves' disease and autoimmune thyroiditis), and mood disorders (major...

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Diabetes and associated disorders
Genetic Associations and Epidemiology
Thyroid Disorders and Treatments

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40081583
DOI: 10.1016/j.jad.2025.03.033

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