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Article

Clear cell renal cell carcinoma with prominent microvascular hyperplasia: Morphologic, immunohistochemical and molecular-genetic analysis of 7 sporadic cases.

Annals of diagnostic pathology - 1 Feb 2022

Alaghehbandan Reza, Limani Rinë, Ali Leila, Rogala Joanna, Vanecek Tomas, Steiner Petr, Hajkova Veronika, Kuthi Levente, Slisarenko Maryna, Michalova Kvetoslava, Pivovarcikova Kristyna, Hora Milan, Pitra Tomas, Michal Michal, Hes Ondrej

Abstract excerpt

Clear cell renal cell carcinoma (CCRCC) is well known for intratumor heterogeneity. An accurate mapping of the tumor is crucial for assessing prognosis, and perhaps this can be linked to potential success/failure of targeted therapies. We assembled a cohort of 7 CCRCCs with prominent vasculature and microvascular hyperplasia (ccRCCPV), resembling those seen in high grade gliomas. A control group of classic CCRCC...

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PMID: 34847388
DOI: 10.1016/j.anndiagpath.2021.151871

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