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Comprehensive review of chromophobe renal cell carcinoma

20 Mar 2021

Abstract excerpt

Chromophobe renal cell carcinoma (chRCC) is the third most common type of RCC with distinct biology compared to other kidney cancer subtypes. The heterogeneity between the RCC subtypes is associated with noticeable differences in tumor aggressiveness and risk for the development of metastatic disease. ChRCC is characterized by chromosomal aneuploidy, TP53, PTEN, and mitochondrial gene mutations. Though the...

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PMID: 33753250
DOI: 10.1016/j.critrevonc.2021.103287

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