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Walking down Skeletal Muscle Lane: From Inflammasome to Disease

4 Nov 2021

Abstract excerpt

Over the last decade, innate immune system receptors and sensors called inflammasomes have been identified to play key pathological roles in the development and progression of numerous diseases. Among them, the nucleotide-binding oligomerization domain (NOD-), leucine-rich repeat (LRR-) and pyrin domain-containing protein 3 (NLRP3) inflammasome is probably the best characterized. To date, NLRP3 has been...

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PMID: 34831246
DOI: 10.3390/cells10113023

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