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Article

Inflammasome in ALS Skeletal Muscle: NLRP3 as a Potential Biomarker

3 Mar 2021

Abstract excerpt

Since NLRP3 inflammasome plays a pivotal role in several neurodegenerative disorders, we hypothesized that levels of inflammasome components could help in diagnosis or prognosis of amyotrophic lateral sclerosis (ALS). Gene and protein expression was assayed by RT-PCR and Western blot. Spearman’s correlation coefficient was used to determine the linear correlation of transcriptional expression levels with...

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PMID: 33802349
DOI: 10.3390/ijms22052523

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