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Inflammasomes and idiopathic inflammatory myopathies

11 Dec 2024

Abstract excerpt

Idiopathic inflammatory myopathies (IIM) are a group of systemic autoimmune diseases characterized by muscle weakness and elevated serum creatine kinase levels. Recent research has highlighted the role of the innate immune system, particularly inflammasomes, in the pathogenesis of IIM. This review focuses on the role of inflammasomes, specifically NLRP3 and AIM2, and their associated proteins in the development...

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PMID: 39723212
DOI: 10.3389/fimmu.2024.1449969

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