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Article

Prokineticin 2 Plays a Pivotal Role in Psoriasis

19 Oct 2016

Abstract excerpt

Psoriasis is histologically characterized by keratinocytes (KC) hyperproliferation, inflammation, and increased angiogenesis, but the pathological factor responsible for these symptoms is unknown. Here, a neuroendocrine peptide (prokineticin 2, PK2), is highly expressed in human and mouse psoriatic skins but no significant change in other autoimmune diseases, suggesting that PK2 is a psoriasis-specific factor....

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Identifiers

PMID: 27887936
DOI: 10.1016/j.ebiom.2016.10.022

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