Article
MOSES: A New Approach to Integrate Interactome Topology and Functional Features for Disease Gene Prediction.
Genes - 27 Oct 2021
Petti Manuela, Farina Lorenzo, Francone Federico, Lucidi Stefano, Macali Amalia, Palagi Laura, De Santis Marianna
Abstract excerpt
Disease gene prediction is to date one of the main computational challenges of precision medicine. It is still uncertain if disease genes have unique functional properties that distinguish them from other non-disease genes or, from a network perspective, if they are located randomly in the interactome or show specific patterns in the network topology. In this study, we propose a new method for disease gene...
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