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Article

Genetic and methylation status of CDKN2A (p14ARF/p16INK4A) and TP53 genes in recurrent respiratory papillomatosis.

Human pathology - 1 Jan 2022

Chantre-Justino Mariana, Gonçalves da Veiga Pires Ingrid, Cardoso Figueiredo Marcelo, Dos Santos Moreira Aline, Alves Gilda, Faria Ornellas Maria Helena

Abstract excerpt

Recurrent respiratory papillomatosis (RRP) is a rare and chronic disease affecting the upper airway with papillomatous lesions caused by the human papillomavirus (HPV) infection, especially HPV-6 and/or HPV-11 types. Little is known about the genetic and epigenetic drivers in RRP pathophysiology. For this purpose, we analyzed 27 papillomatous lesions from patients with RRP to evaluate somatic mutations and...

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Identifiers

PMID: 34826422
DOI: 10.1016/j.humpath.2021.11.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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