Article
Clinical, virological, and immunohistochemical features of laryngeal papilloma with low-risk human papillomavirus infection: insights from a 13-year institutional cohort.
World journal of surgical oncology - 3 Jan 2026
Hirakawa Hitoshi, Ikegami Taro, Kise Norimoto, Kiyuna Asanori, Kinjyo Hidetoshi, Kondo Shunsuke, Nakasone Waku, Maeda Hiroyuki, Agena Shinya, Suzuki Mikio
Abstract excerpt
BACKGROUND: Laryngeal papilloma (LP) is driven primarily by infection with low-risk human papillomavirus (LR-HPV), most often types 6 and 11. However, the clinical relevance of the HPV genotype, viral load, and associated molecular markers in LP remains incompletely understood. METHODS: We retrospectively analyzed 30 patients with LP treated at the University of Ryukyu Hospital between 2010 and 2023. Their tumor...
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