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Article

Genomic diversity of HPV6 and HPV11 in recurrent respiratory papillomatosis: Association with malignant transformation in the lungs and clinical outcomes.

Tumour virus research - 1 Dec 2024

Rahmoun Massilva, Aussel Audrey, Bouzidi Sarah, Pedergnana Vincent, Malassigné Victor, Puech Julien, Veyer David, Péré Hélène, Lepine Charles, Blanc Fabian, Boulle Nathalie, Costes-Martineau Valérie, Bravo Ignacio G

Abstract excerpt

Recurrent respiratory papillomatosis (RRP) is a rare, proliferative disease caused by human papillomavirus 6 (HPV6) and HPV11. RRP can occasionally spread and undergo malignant transformation. We analysed samples across time for five RRP patients with malignant transformation and four with highly recurrent, non-malignant RRP by applying high-throughput sequencing. Patients with malignant transformation were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39481538
DOI: 10.1016/j.tvr.2024.200294
PMCID: PMC11564036

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