Article
Association of GSTO1, GSTO2, GSTP1, GPX1 and SOD2 polymorphism with primary open angle glaucoma.
Experimental eye research - 1 Jan 2022
Sobot Vesna, Stamenkovic Miroslav, Simic Tatjana, Jerotic Djurdja, Djokic Milica, Jaksic Vesna, Bozic Marija, Milic Jovan, Savic-Radojevic Ana, Djukic Tatjana
Abstract excerpt
It is becoming increasingly evident that oxidative stress has a supporting role in pathophysiology and progression of primary open angle glaucoma (POAG). The aim of our study was to assess the association between polymorphisms in genes encoding enzymes involved in redox homeostasis, mitochondrial superoxide dismutase (SOD2), glutathione peroxidase (GPX1) and glutathione transferases (GSTs) with susceptibility to...
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