Article
The role of Cat -262C/T, GPX1 Pro198Leu and Sod1+35A/C gene polymorphisms in a development of primary open-angle glaucoma in a Polish population.
Polish journal of pathology : official journal of the Polish Society of Pathologists - 1 Jan 2000
Malinowska Katarzyna, Kowalski Michał, Szaflik Jerzy, Szaflik Jerzy P, Majsterek Ireneusz
Abstract excerpt
The development of glaucoma may be connected with a long-term exposure to oxidative stress caused by free radical (ROS). The main aim of this work was an analysis of associations of Cat-262C/T, GPX1 Pro198Leu and SOD1 35 A/C gene polymorphisms of antioxidant enzymes with a risk of open-angle glaucoma (POAG) in a Polish population. DNA samples collected from 209 patients with POAG and 191 healthy controls were...
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