Article
Colony Stimulating Factor 3 Mutations and Myeloid Malignancies.
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Feb 2016
Xing Yi, Zhao Ming-feng
Abstract excerpt
Granulocyte colony stimulating factor (G-CSF) plays a major role in the proliferation, differentiation, and activation of neutrophil cell line hematopoietic cells. G-CSF exert the function depending on its binding to colony-stimulating factor 3 receptor (CSF3R), a homo-dimer receptor located on the surface of effector cells. Some recent studies have demonstrated that CSF3R mutations play a significant role in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
