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Targeting oncogene-induced cellular plasticity for tumor therapy

15 Jul 2024

Abstract excerpt

Cellular plasticity, the remarkable adaptability of cancer cells to survive under various stress conditions, is a fundamental hallmark that significantly contributes to treatment resistance, tumor metastasis, and disease recurrence. Oncogenes, the driver genes that promote uncontrolled cell proliferation, have long been recognized as key drivers of cellular transformation and tumorigenesis. Paradoxically,...

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PMID: 39883338
DOI: 10.1007/s44307-024-00030-y

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