Article
Drugs and addiction: an introduction to epigenetics.
Addiction (Abingdon, England) - 1 Mar 2011
Wong Chloe C Y, Mill Jonathan, Fernandes Cathy
Abstract excerpt
Addiction is a debilitating psychiatric disorder, with a complex aetiology involving the interaction of inherited predispositions and environmental factors. Emerging evidence suggests that epigenetic alterations to the genome, including DNA methylation and histone modifications, are important mechanisms underlying addiction and the neurobiological response to addictive substances. In this review, we introduce the...
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