Article
Epigenetic inheritance of phenotypes associated with parental exposure to cocaine.
Advances in pharmacology (San Diego, Calif.) - 1 Jan 2024
Rich Matthew T, Swinford-Jackson Sarah E, Pierce R Christopher
Abstract excerpt
Parental exposure to drugs of abuse induces changes in the germline that can be transmitted across subsequent generations, resulting in enduring effects on gene expression and behavior. This transgenerational inheritance involves a dynamic interplay of environmental, genetic, and epigenetic factors that impact an individual's vulnerability to neuropsychiatric disorders. This chapter aims to summarize recent...
Topics
- Humans
- Cocaine
- Epigenesis, Genetic
- DNA Methylation
- Phenotype
