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Article

Trib1 deficiency causes brown adipose respiratory chain depletion and mitochondrial disorder

22 Nov 2021

Abstract excerpt

Tribbles homolog 1 (TRIB1) belongs to the Tribbles family of pseudokinases, which plays a key role in tumorigenesis and inflammation. Although genome-wide analysis shows that TRIB1 expression is highly correlated with blood lipid levels, the relationship between TRIB1 and adipose tissue metabolism remains unclear. Accordingly, the aim of the present study was to explore the role of TRIB1 on mitochondrial function...

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Share to Adipose Tissue and Metabolism
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PMID: 34811364
DOI: 10.1038/s41419-021-04389-x

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