Article
CYP4V2 fatty acid omega hydroxylase, a druggable target for the treatment of metabolic associated fatty liver disease (MAFLD).
Biochemical pharmacology - 1 Jan 2022
Osborne Nicholas, Leahy Charles, Lee Yoon-Kwang, Rote Paula, Song Byoung-Joon, Hardwick James P
Abstract excerpt
Fatty acids are essential in maintaining cellular homeostasis by providing lipids for energy production, cell membrane integrity, protein modification, and the structural demands of proliferating cells. Fatty acids and their derivatives are critical bioactive signaling molecules that influence many cellular processes, including metabolism, cell survival, proliferation, migration, angiogenesis, and cell barrier...
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