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Article

Accumulation of Lipid Droplets in a Novel Bietti Crystalline Dystrophy Zebrafish Model With Impaired PPARα Pathway.

Investigative ophthalmology & visual science - 2 May 2022

Gao Pan, Jia Danna, Li Pei, Huang Yuwen, Hu Hualei, Sun Kui, Lv Yuexia, Chen Xiang, Han Yunqiao, Zhang Zuxiao, Ren Xiang, Wang Qing, Liu Fei, Tang Zhaohui, Liu Mugen

Abstract excerpt

Purpose: Bietti crystalline dystrophy (BCD) is a progressive retinal degenerative disease primarily characterized by numerous crystal-like deposits and degeneration of retinal pigment epithelium (RPE) and photoreceptor cells. CYP4V2 (cytochrome P450 family 4 subfamily V member 2) is currently the only disease-causing gene for BCD. We aimed to generate a zebrafish model to explore the functional role of CYP4V2 in...

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Share to Corneal Dystrophies, Hereditary
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35616930
DOI: 10.1167/iovs.63.5.32
PMCID: PMC9150832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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