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Article

Pancreatic Cancer-Related Mutational Burden Is Not Increased in a Patient Cohort With Clinically Severe Chronic Pancreatitis.

Clinical and translational gastroenterology - 18 Nov 2021

Cowan Robert W, Pratt Erica D, Kang Jin Muk, Zhao Jun, Wilhelm Joshua J, Abdulla Muhamad, Qiao Edmund M, Brennan Luke P, Ulintz Peter J, Bellin Melena D, Rhim Andrew D

Abstract excerpt

INTRODUCTION: Chronic pancreatitis is associated with an increased risk of developing pancreatic cancer, and patients with inherited forms of pancreatitis are at greatest risk. We investigated whether clinical severity of pancreatitis could also be an indicator of cancer risk independent of etiology by performing targeted DNA sequencing to assess the mutational burden in 55 cancer-associated genes. METHODS: Using...

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Identifiers

PMID: 34797250
DOI: 10.14309/ctg.0000000000000431
PMCID: PMC8604013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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