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Article

Comparison of clinical features and pancreatic cancer risk between genetic mutations associated versus alcohol associated chronic pancreatitis.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Feb 2026

Lee Yoonchan, Song Tae Jun, Cho Sung Hyun, Huh Gunn, Oh Dongwook, Seo Dong-Wan

Abstract excerpt

BACKGROUND/OBJECTIVES: Genetic mutations associated chronic pancreatitis (GCP), caused by pathogenic variants in SPINK1, PRSS1, or CFTR, represents a distinct subset of chronic pancreatitis, whereas alcoholic chronic pancreatitis (ACP) is the predominant adult etiology. We compared the clinical course and pancreatic cancer risk between GCP and ACP. METHODS: This retrospective cohort included GCP patients from a...

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Source

Identifiers

PMID: 41198504
DOI: 10.1016/j.pan.2025.10.011

Genes

SPINK1
CFTR
PRSS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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