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Article

KRAS mutations in blood circulating cell-free DNA: a pancreatic cancer case-control.

Oncotarget - 29 Nov 2016

Le Calvez-Kelm Florence, Foll Matthieu, Wozniak Magdalena B, Delhomme Tiffany M, Durand Geoffroy, Chopard Priscilia, Pertesi Maroulio, Fabianova Eleonora, Adamcakova Zora, Holcatova Ivana, Foretova Lenka, Janout Vladimir, Vallee Maxime P, Rinaldi Sabina, Brennan Paul, McKay James D, Byrnes Graham B, Scelo Ghislaine

Abstract excerpt

The utility of KRAS mutations in plasma circulating cell-free DNA (cfDNA) samples as non-invasive biomarkers for the detection of pancreatic cancer has never been evaluated in a large case-control series. We applied a KRAS amplicon-based deep sequencing strategy combined with analytical pipeline specifically designed for the detection of low-abundance mutations to screen plasma samples of 437 pancreatic cancer...

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Source

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Identifiers

PMID: 27705932
DOI: 10.18632/oncotarget.12386
PMCID: PMC5346680

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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