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Progression of Chronic Pancreatitis to Pancreatic Cancer: Is There a Role of Gene Mutations as a Screening Tool?

Pancreas - 1 Feb 2018

Rashid Sumaira, Singh Nidhi, Gupta Surabhi, Rashid Safoora, Nalika Nandini, Sachdev Vikas, Bal Chandra Sekhar, Datta Gupta Siddhartha, Chauhan Shyam S, Saraya Anoop

Abstract excerpt

OBJECTIVES: Early detection of pancreatic ductal adenocarcinoma still remains a challenge. Patients with chronic pancreatitis (CP) have a markedly increased risk of pancreatic cancer. Mutations in oncogenes and/or tumor suppressor genes play a role in development of pancreatic ductal adenocarcinoma. This study assessed mutations in KRAS and p53 gene in blood as a screening tool for malignant transformation in CP...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins p21(ras)

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Source

Identifiers

PMID: 29303908
DOI: 10.1097/MPA.0000000000000975

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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