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Article

Diet-Derived Antioxidants Do Not Decrease Risk of Ischemic Stroke: A Mendelian Randomization Study in 1 Million People.

Journal of the American Heart Association - 7 Dec 2021

Martens Leon G, Luo Jiao, Willems van Dijk Ko, Jukema J Wouter, Noordam Raymond, van Heemst Diana

Abstract excerpt

Background Dietary intake and blood concentrations of vitamins E and C, lycopene, and carotenoids have been associated with a lower risk of incident (ischemic) stroke. However, causality cannot be inferred from these associations. Here, we investigated causality by analyzing the associations between genetically influenced antioxidant levels in blood and ischemic stroke using Mendelian randomization. Methods and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34796734
DOI: 10.1161/JAHA.121.022567
PMCID: PMC9075393

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