Article
Circulating antioxidants and Alzheimer disease prevention: a Mendelian randomization study.
The American journal of clinical nutrition - 1 Jan 2019
Williams Dylan M, Hägg Sara, Pedersen Nancy L
Abstract excerpt
Background: Higher circulating antioxidant concentrations are associated with a lower risk of late-onset Alzheimer disease (AD) in observational studies, suggesting that diet-sourced antioxidants may be modifiable targets for reducing disease risk. However, observational evidence is prone to substantial biases that limit causal inference, including residual confounding and reverse causation. Objectives: In order...
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