Article
Investigating Causal Associations of Diet-Derived Circulating Antioxidants with the Risk of Digestive System Cancers: A Mendelian Randomization Study.
Nutrients - 8 Aug 2022
Zhang Xuening, Zhao Hao, Man Jinyu, Yin Xiaolin, Zhang Tongchao, Yang Xiaorong, Lu Ming
Abstract excerpt
Molecular mechanisms and observational studies have found that diet-derived antioxidants are associated with digestive system cancers, whereas there is a lack of causal evidence from randomized clinical trials. In this study, we aimed to assess the causality of these associations through a Mendelian randomization (MR) study. Single nucleotide polymorphisms of diet-derived circulating antioxidants (i.e., α- and...
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