Article
Predictors of decreased bone mineral density in childhood systemic lupus erythematosus: possible role of osteoprotegerin gene polymorphisms.
Journal of pediatric endocrinology & metabolism : JPEM - 27 Jan 2022
Eid Riham, Abdelsalam Maha, Fathy Aya A, Abd-El Ghaffar Dena M, Elmarghany Eman B, El-Hanafy Aya A, Mostafa Nora, Hamdy Nashwa, Niazy Nermeen A, Hammad Ayman, Abolenein Hadil M
Abstract excerpt
OBJECTIVES: This study aims to explore effects of osteoprotegerin (OPG) gene polymorphisms and other possible factors on bone mineral density (BMD) in children with systemic lupus erythematosus (SLE). METHODS: Osteoprotegerin gene rs2073617 and rs3134069 were evaluated in 74 SLE patients and 100 controls then genotypes, alleles and haplotypes' frequencies were compared between cases and controls and between...
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