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Article

Polymorphisms in key bone modulator cytokines genes influence bisphosphonates therapy in postmenopausal women.

Inflammopharmacology - 1 Apr 2017

Lima C A D, Javorski N R, Souza A P O, Barbosa A D, Valença A P M C, Crovella S, Souza P R E, De Azevedo Silva J, Sandrin-Garcia P

Abstract excerpt

Osteoporosis is a multifactorial and debilitating disease resulting from decreased bone mineral density (BMD) and loss of tissue microarchitecture. Ineffective therapies may lead to bone fractures and subsequent death. Single nucleotide polymorphisms (SNPs) in key immune regulator genes have been associated with therapeutic response to bisphosphonates, which are the first therapeutic line of choice for...

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PMID: 28220389
DOI: 10.1007/s10787-017-0322-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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