Article
Organ-specific genome diversity of replication-competent SARS-CoV-2.
Nature communications - 16 Nov 2021
Van Cleemput Jolien, van Snippenberg Willem, Lambrechts Laurens, Dendooven Amélie, D'Onofrio Valentino, Couck Liesbeth, Trypsteen Wim, Vanrusselt Jan, Theuns Sebastiaan, Vereecke Nick, van den Bosch Thierry P P, Lammens Martin, Driessen Ann, Achten Ruth, Bracke Ken R, Van den Broeck Wim, Von der Thüsen Jan, Nauwynck Hans, Van Dorpe Jo, Gerlo Sarah, Maes Piet, Cox Janneke, Vandekerckhove Linos
Abstract excerpt
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is not always confined to the respiratory system, as it impacts people on a broad clinical spectrum from asymptomatic to severe systemic manifestations resulting in death. Further, accumulation of intra-host single nucleotide variants during prolonged SARS-CoV-2 infection may lead to emergence of variants of concern (VOCs). Still, information...
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