Article
Making a Killer: Selecting the Optimal Natural Killer Cells for Improved Immunotherapies.
Frontiers in immunology - 1 Jan 2021
Barnes Samantha A, Trew Isabella, de Jong Emma, Foley Bree
Abstract excerpt
Over the past 20 years natural killer (NK) cell-based immunotherapies have emerged as a safe and effective treatment option for patients with relapsed or refractory leukemia. Unlike T cell-based therapies, NK cells harbor an innate capacity to eliminate malignant cells without prior sensitization and can be adoptively transferred between individuals without the need for extensive HLA matching. A wide variety of...
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