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Article

Identification of Two Subsets of Murine DC1 Dendritic Cells That Differ by Surface Phenotype, Gene Expression, and Function.

Frontiers in immunology - 1 Jan 2021

Hongo David, Zheng Pingping, Dutt Suparna, Pawar Rahul D, Meyer Everett, Engleman Edgar G, Strober Samuel

Abstract excerpt

Classical dendritic cells (cDCs) in mice have been divided into 2 major subsets based on the expression of nuclear transcription factors: a CD8+Irf8+Batf3 dependent (DC1) subset, and a CD8-Irf4+ (DC2) subset. We found that the CD8+DC1 subset can be further divided into CD8+DC1a and CD8+DC1b subsets by differences in surface receptors, gene expression, and function. Whereas all 3 DC subsets can act alone to induce...

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Identifiers

PMID: 34777358
DOI: 10.3389/fimmu.2021.746469
PMCID: PMC8589020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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