Article
Lysine acetylation regulates the interaction between proteins and membranes.
Nature communications - 9 Nov 2021
Okada Alan K, Teranishi Kazuki, Ambroso Mark R, Isas Jose Mario, Vazquez-Sarandeses Elena, Lee Joo-Yeun, Melo Arthur Alves, Pandey Priyatama, Merken Daniel, Berndt Leona, Lammers Michael, Daumke Oliver, Chang Karen, Haworth Ian S, Langen Ralf
Abstract excerpt
Lysine acetylation regulates the function of soluble proteins in vivo, yet it remains largely unexplored whether lysine acetylation regulates membrane protein function. Here, we use bioinformatics, biophysical analysis of recombinant proteins, live-cell fluorescent imaging and genetic manipulation of Drosophila to explore lysine acetylation in peripheral membrane proteins. Analysis of 50 peripheral membrane...
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