Article
Liquid biopsy in diffuse large B-cell lymphoma: utility in cell origin determination and survival prediction in Chinese patients.
Leukemia & lymphoma - 1 Mar 2022
Li Miaomiao, Ding Ning, Mi Lan, Shi Yunfei, Du Xinhua, Yi Yuting, Yang Ling, Liu Weiping, Zhu Jun
Abstract excerpt
The utility of circulating tumor DNA (ctDNA) in classifying the cell origin of diffuse large B-cell lymphoma (DLBCL) has not been explored in the Chinese population. In this study, we aimed to investigate the genetic characteristics of DLBCL based on both tumor and ctDNA sequencing and to assess the predictive value of ctDNA in DLBCL. A targeted sequencing panel of 413 genes was applied to tumor biopsies and...
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