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Article

Clinical implications of cell-of-origin epigenetic characteristics in non-functional pancreatic neuroendocrine tumors.

The Journal of pathology - 1 Feb 2022

Dreijerink Koen Ma, Hackeng Wenzel M, Singhi Aatur D, Heaphy Christopher M, Brosens Lodewijk Aa

Abstract excerpt

Primary non-functional pancreatic neuroendocrine tumors (NF-PanNETs) are a heterogeneous group of neuroendocrine neoplasms that display highly variable clinical behavior. Therefore, NF-PanNETs often present clinical teams with a dilemma: the uncertain metastatic potential of the tumor has to be weighed against the morbidity associated with surgical resection. Thus, rather than utilizing current radiologic...

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Source

Identifiers

PMID: 34750813
DOI: 10.1002/path.5834

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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